1 1,298 343 774 1 Uncharacterized alpha/beta hydrolase domain (DUF2235):774
Bacteria 0 504 2 1,240 1,101 1,238 1 2-hydroxy-palmitic acid dioxygenase Mpo1-like:1,238
Eukaryota 2 197 3 1,222 1,146 703 2 Protein of unknown function (DUF2408):702
MIF4G domain:1
Viridiplantae 0 461 4 1,219 1,185 1,219 1 Uncharacterised protein family (UPF0160):1,219
Eukaryota 0 352 5 1,154 1,138 509 7 HEAT repeat:494
HEAT-like repeat:9
Adaptin N terminal region:4
HEAT repeats:1
Damage-control phosphatase ARMT1-like domain:1
Alpha-L-rhamnosidase N-terminal domain:1
DNA/RNA non-specific endonuclease:1
Viridiplantae 0 2,039 6 1,127 1,110 1,127 3 Domain of unknown function (DUF383):1,126
Domain of unknown function (DUF384):1,122
SecE/Sec61-gamma subunits of protein translocation complex:1
Opisthokonta + Viridiplantae 0 390 7 1,120 1,093 1,119 1 Hikeshi-like, N-terminal domain:1,119
Opisthokonta + Viridiplantae 0 214 8 1,116 1,051 1,116 1 2-phospho-L-lactate transferase CofD:1,116
Eukaryota 0 496 9 1,072 1,045 1,053 1 CXXC motif containing zinc binding protein, eukaryotic:1,053
Opisthokonta 1 162 10 1,080 961 560 1 Protein of unknown function (DUF4449):560
Viridiplantae 0 866 11 1,083 1,071 209 6 HEAT repeat:202
Cse1:4
Ankyrin repeats (3 copies):1
Ssl1-like:1
RNase P subunit Pop3:1
Ankyrin repeat:1
Viridiplantae 1 1,118 12 1,033 1,015 981 9 TPR repeat:481
Tetratricopeptide repeat:454
Tetratricopeptide repeat:336
Tetratricopeptide repeat:37
Tetratricopeptide repeat:10
Tetratricopeptide repeat:7
NUDIX domain:4
Tetratricopeptide repeat:4
Tetratricopeptide repeat:2
Eukaryota 0 936 13 1,023 714 5 1 Lipocalin / cytosolic fatty-acid binding protein family:5
0 194 14 1,024 820 565 1 Domain of unknown function (DUF4149):565
Viridiplantae 1 182 15 1,014 758 1,013 1 Gig2-like:1,013
Universal 0 477 16 936 928 2 2 L27 domain:1
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family:1
Viridiplantae 0 510 17 927 673 567 5 Protein of unknown function (DUF3292):566
Integral peroxisomal membrane peroxin:1
Plant phosphoribosyltransferase C-terminal:1
HIUase/Transthyretin family:1
Profilin:1
0 674 18 857 833 854 2 NFACT protein RNA binding domain:854
YacP-like NYN domain:1
Eukaryota 0 215 19 857 809 857 1 Protein of unknown function (DUF1348):857
Universal 0 157 20 789 777 782 2 Eukaryotic integral membrane protein (DUF1751):782
Rhomboid family:1
Viridiplantae 0 370 21 794 633 485 1 Questin oxidase-like:485
Viridiplantae 0 419 22 762 738 446 2 Uncharacterized protein conserved in bacteria (DUF2264):445
Transcription factor WhiB:1
Prokaryotes 0 649 23 746 736 709 6 UBA/TS-N domain:508
TPR repeat:364
Tetratricopeptide repeat:52
Tetratricopeptide repeat:22
DnaJ domain:4
Chaperonin 10 Kd subunit:1
Opisthokonta + Viridiplantae 1 913 24 751 733 0 0 0 119 25 748 740 748 3 Protein adenylyltransferase SelO:748
Ankyrin repeats (3 copies):1
Leucine Rich Repeat:1
Universal 0 633 26 745 701 726 1 Protein of unknown function (DUF1769):726
Viridiplantae 0 323 27 725 715 716 1 Armadillo-like helical domain-containing protein 3, C-terminal:716
Opisthokonta + Viridiplantae 0 644 28 720 713 14 1 Bridge-like lipid transfer protein family member 1, C-terminal:14
Viridiplantae + Bacteria 1 3,197 29 712 707 637 3 THADA/TRM732, DUF2428:384
HEAT repeat:255
HEAT-like repeat:4
0 1,599 30 707 700 700 1 PAT complex subunit CCDC47:700
Viridiplantae + Bacteria 1 436 31 699 630 412 3 Fungal protein of unknown function (DUF1752):412
SGF29 tudor-like domain:5
Protein of unknown function (DUF3295):1
Viridiplantae 0 559 32 703 701 270 6 Ankyrin repeat:162
Ankyrin repeats (many copies):106
Ankyrin repeats (3 copies):1
Zinc finger, C2H2 type:1
Ubiquitin interaction motif:1
Ankyrin repeat:1
Viridiplantae 1 646 33 683 674 387 2 DENN domain-containing protein 11:387
Domain of unknown function (DUF4484):387
Viridiplantae 0 606 34 677 669 255 2 Protein of unknown function (DUF3712):254
BTB/POZ domain:1
Viridiplantae 0 855 35 661 658 622 3 WD domain, G-beta repeat:622
Nup133 N terminal like:1
Nucleoporin Nup120/160:1
Viridiplantae 0 510 36 634 600 33 2 NAD dependent epimerase/dehydratase family:25
NAD(P)H-binding:8
0 300 37 659 653 659 1 Protein of unknown function (DUF1295):659
Universal 0 363 38 658 654 51 1 Protein of unknown function (DUF4449):51
Viridiplantae 0 743 39 659 645 5 1 SKG6 family:5
Opisthokonta 0 713 40 652 646 5 3 Putative peptidoglycan binding domain:2
Tim10/DDP family zinc finger:2
Myosin tail:1
Viridiplantae 1 876 41 655 634 17 6 Galactose oxidase, central domain:6
Kelch motif:6
Glycophorin A:2
Herpesvirus glycoprotein D/GG/GX domain:1
Kelch motif:1
Galactose oxidase, central domain:1
Viridiplantae 0 751 42 649 643 0 0 Viridiplantae 1 966 43 651 637 0 0 0 351 44 649 645 1 1 SOS response associated peptidase (SRAP):1
0 390 45 651 648 0 0 Viridiplantae 0 563 46 648 638 2 1 S25 ribosomal protein:2
Viridiplantae 0 768 47 629 467 2 1 Fungal protein of unknown function (DUF1774):2
0 273 48 646 644 0 0 1 553 49 641 637 485 10 Tetratricopeptide repeat:247
Tetratricopeptide repeat:111
TPR repeat:61
Tetratricopeptide repeat:51
Tetratricopeptide repeat:10
Tetratricopeptide repeat:9
Tetratricopeptide repeat:5
Tetratricopeptide repeat:3
Tetratricopeptide repeat:2
Tetratricopeptide repeat:2
Viridiplantae 0 322 50 645 640 0 0 0 274 51 645 641 0 0 0 302 52 645 640 0 0 Viridiplantae 0 328 53 634 630 5 1 ATPase family associated with various cellular activities (AAA):5
Viridiplantae 0 368 54 641 633 3 2 Metallo-beta-lactamase superfamily:2
Mitochondrial carrier protein:1
Viridiplantae + Bacteria 0 1,694 55 638 631 346 1 WD domain, G-beta repeat:346
Viridiplantae 0 423 56 637 630 0 0 Viridiplantae 3 453 57 638 631 350 3 Armadillo/beta-catenin-like repeat:324
HEAT repeat:56
HEAT repeats:4
Opisthokonta + Viridiplantae 0 1,020 58 634 629 0 0 3 433 59 633 623 0 0 Viridiplantae 0 429 60 635 627 1 1 Ubiquitin fusion degradation protein UFD1:1
Viridiplantae + Cryptophyta 1 841 61 636 619 0 0 0 946 62 638 635 360 1 DnaJ homologue, subfamily C, member 28, conserved domain:360
Viridiplantae 0 522 63 629 624 349 1 PF08217:349
Viridiplantae 0 828 64 631 627 0 0 0 455 65 629 626 2 1 30S ribosomal protein subunit S22 family:2
Viridiplantae 2 448 66 625 622 10 1 SnoaL-like polyketide cyclase:10
Viridiplantae 0 551 67 624 621 357 1 Domain of unknown function (DUF4078):357
Viridiplantae 0 358 68 624 612 1 1 Protein of unknown function (DUF4030):1
0 138 69 622 618 30 1 Telomere attrition and p53 response 1 protein-like:30
0 264 70 620 617 0 0 Viridiplantae 0 643 71 619 616 0 0 0 369 72 620 617 0 0 Bacteria 0 357 73 621 615 0 0 0 441 74 621 614 1 1 PQ loop repeat:1
0 1,106 75 616 606 2 2 Plethodontid receptivity factor PRF:1
emp24/gp25L/p24 family/GOLD:1
Viridiplantae 0 1,298 76 618 615 0 0 0 559 77 619 613 0 0 Viridiplantae + Bacteria 0 499 78 619 610 361 1 Domain of unknown function (DUF4452):361
Viridiplantae 0 195 79 621 615 361 1 Domain of unknown function (DUF4604):361
0 171 80 616 610 6 2 Bombesin-like peptide:5
Serine incorporator (Serinc):1
0 303 81 615 608 202 3 GATA zinc finger:195
AT hook motif:11
Fungal Zn(2)-Cys(6) binuclear cluster domain:6
Viridiplantae + Bacteria 0 1,233 82 614 609 351 1 Protein of unknown function (DUF2418):351
Viridiplantae 0 461 83 612 610 1 1 AIR carboxylase:1
0 598 84 614 608 130 5 Tetratricopeptide repeat:125
Coatomer epsilon subunit:2
Tetratricopeptide repeat:1
Tetratricopeptide repeat:1
Tetratricopeptide repeat:1
Viridiplantae 0 440 85 611 607 0 0 0 549 86 608 605 0 0 0 908 87 610 607 3 2 SAP domain:2
Rho termination factor, N-terminal domain:1
0 353 88 545 342 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2):1
0 335 89 529 476 529 1 Uncharacterized protein family UPF0016:529
Eukaryota 1 276 90 490 471 488 1 Integral membrane protein DUF92:488
Eukaryota 0 309 91 485 314 1 1 COPI associated protein:1
0 277 92 469 454 469 1 Uncharacterised protein family UPF0047:469
Universal 0 141 93 439 427 77 4 Ankyrin repeat:59
Ankyrin repeats (many copies):11
Ankyrin repeat:6
Ankyrin repeats (many copies):1
Opisthokonta 1 659 94 447 416 447 1 Protein of unknown function (DUF1295):447
Universal 0 359 95 433 423 431 1 PAT complex subunit CCDC47:431
1 373 96 418 408 222 1 Uncharacterized conserved protein (DUF2340):222
Eukaryota 1 142 97 414 380 0 0 1 263 98 409 350 22 2 PhoD-like phosphatase:21
Cytochrome c oxidase subunit Vb:1
Opisthokonta + Viridiplantae + Bacteria 0 700 99 401 374 64 2 Armadillo/beta-catenin-like repeat:63
HEAT repeat:1
0 676 100 395 387 332 4 WD domain, G-beta repeat:330
WD40-like Beta Propeller Repeat:4
Eukaryotic translation initiation factor eIF2A:1
60s Acidic ribosomal protein:1
Eukaryota 0 503 101 383 373 382 2 Eukaryotic integral membrane protein (DUF1751):382
Der1-like family:1
2 356 102 385 374 197 2 Cell wall protein YJL171C/Tos1, C-terminal:197
Cell wall protein YJL171C/Tos1, N-terminal:197
Viridiplantae + Archaea 1 467 103 381 329 43 2 GDSL-like Lipase/Acylhydrolase family:36
GDSL-like Lipase/Acylhydrolase:7
1 567 104 372 357 0 0 1 318 105 370 366 92 1 Armadillo/beta-catenin-like repeat:92
0 696 106 375 365 375 2 Protein adenylyltransferase SelO:375
Rpp14/Pop5 family:3
Universal 0 725 107 355 352 2 1 SPT2 chromatin protein:2
0 3,248 108 352 348 1 1 AT hook motif:1
0 993 109 341 335 0 0 0 785 110 337 317 1 1 Kelch motif:1
0 388 111 338 318 0 0 0 636 112 342 328 88 2 BTB/POZ domain:48
MATH domain:41
0 610 113 333 309 0 0 0 472 114 331 315 1 1 UreD urease accessory protein:1
0 873 115 330 319 0 0 1 441 116 326 312 0 0 0 237 117 321 319 186 1 Protein of unknown function (DUF2418):186
0 390 118 318 308 139 2 V-type proton ATPase subunit S1, luminal domain:138
PF08319:1
0 283 119 320 315 0 0 0 375 120 313 309 12 2 Arrestin (or S-antigen), C-terminal domain:9
Eukaryotic protein of unknown function (DUF1764):3
0 663 121 299 271 170 2 Protein of unknown function (DUF3712):170
Ribosomal RNA adenine dimethylase:1
Bacteria 0 2,401 122 305 290 152 2 Ykl077w/Psg1 (Pma1 Stabilization in Golgi):151
Amino acid permease:1
0 545 123 190 56 22 1 MAPEG family:22
0 173 124 178 155 177 1 Coiled-coil domain-containing protein 90-like:177
Opisthokonta 1 204 125 155 100 155 1 CYRIA/CYRIB Rac1 binding domain:155
Eukaryota 0 328 126 107 76 81 5 Protein of unknown function (DUF3684):78
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase:12
CUE domain:4
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase:2
TLD:1
Eukaryota 0 1,680 127 83 55 0 0 0 262 128 92 84 0 0 0 589 129 82 79 82 1 Uncharacterised protein family (UPF0203):82
Universal 0 83 130 66 62 0 0 0 281 131 66 61 2 1 MIOREX complex component 7:2
0 70 132 68 55 18 1 Uncharacterised protein (DUF2406):18
0 190 133 59 27 1 1 Cytochrome c oxidase assembly protein PET191:1
0 537 134 44 30 0 0 0 380 135 37 33 9 1 Armadillo/beta-catenin-like repeat:9
0 943 136 36 36 1 1 YLP motif:1
0 557 137 34 34 6 3 Ankyrin repeats (many copies):3
Ankyrin repeat:2
Glycolipid 2-alpha-mannosyltransferase:1
Viridiplantae 0 818 138 28 26 6 1 Perilipin family:6
0 298 139 27 26 16 2 Meiotically up-regulated protein Msb1/Mug8 domain:12
RhoGAP domain:4
0 1,410 140 27 25 4 3 Leucine Rich Repeat:2
Leucine Rich Repeat:1
Leucine Rich repeat:1
0 905 141 26 26 10 1 PF13345:10
0 652 142 25 25 0 0 0 346