Peptidases • Suillus
Annotations/GenomesSuiFC429_1Suiame1Suiamp1Suibov1Suibr2Suicli1Suicol1Suicot1Suidec1Suidis1Suielb1Suifus1Suigr1Suihi1Suilak1Suilu4Suiocc1Suioch1Suipal1Suipic1Suipla1Suiplac1Suiplo1Suipse1Suipun1Suipunc1Suiqui1Suisib1Suisu1Suisub1Suisubl1Suitom1Suivar1Suivari1TotalAnnotation Description
Merops
32534236130751232731738459833534233937140037628729134534467128526931329626530727937535031638735831932612,019
66496351606247582546769515373673939535435439365740395150596657605550612,349Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112112111112122212211122121111221248Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
16152115141716261715171616141613131918191616121415131417191719151414548Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6109107127969977897671076610778791181213913288Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2111111212122314127Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Water nucleophile; water bound by Gln and Glu; all endopeptidases
322222222226232222222222222223222275Families of peptidase inhibitors not assigned to clans
123
112
111111121111111117
22322342221222113322221221212222266
222222222222222222222221222222222267Families of metallopeptidases not assigned to clans
1111121112171017131211111212161014101113111112128101219131014131413418Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112111111213211121111121111111211142Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112444511156136Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
8119781010978610710118119109127109787107981099300Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
18161914162216191817231714162015172120171513171515181525161816162215591Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1313111518121620151616121314171318141616141513191114121614720131412492Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111311111111111111111111111111136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5655556557685855555655555655555766187Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111111111111111111121Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
1111141212211112225Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
20212022212123222321202519222120212019222221212218212120222124232121721Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
55345656445465564651254564554555444170Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
9101398781210910118878109111478897127111110141089322Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
92101128989491105127961051021057997122808711611912195879991798786113106931251051031033,437Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
13111113511121311113111311651611162Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
53645453443846103455444534543646633155Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11214312Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111111111111111111111111111111134Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3433334434334323433333444344434334115Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111112111111121111111111112137
285020242181521261032322301088621402130203216171824272219362032295126241,299
1113
112