Peptidases • Penicillium sp. NC0857 v1.0
Annotations/GenomesAspni7Aspzo1Monru1Paevar1Pench1Talpro1Theau1ThyNC0857_1TotalAnnotation Description
Merops
3883142622602955272143012,561
159999311018110Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1124Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
8838787655Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3435342833332732256Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3333253325Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1121121110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
53264132540Water nucleophile; water bound by Gln and Glu; all endopeptidases
5655555541Families of peptidase inhibitors not assigned to clans
11
1124
112
121311110
4233352325
76333133745Families of metallopeptidases not assigned to clans
141379101211985Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
84779106859Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2616211125231222156Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
17131381122812104Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
5132432222Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11125Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2020202320202220165Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
8672883547Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1315Serine or threonine nucleophile; N-terminal nucleophile
1299471951681Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1601217491922315882909Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1059710233673Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3223542425Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2221221214Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
1222122113Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
33111211Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
91112910991584
123
112
536345430