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Peptidases • Microbotryum lychnidis-dioicae p1A1 Lamole
Annotations/GenomesHetpy1Hyabl1Leucr1Mereb1Micld1Rhoto1Spopa1Sporo1TotalAnnotation Description
Merops
1721812302911901831801581,585
1212143016111511121Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1122232215Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2221201911161416139Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3323222219Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12216Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2223223319Families of peptidase inhibitors not assigned to clans
11
11114
11
11
2226232120
11111218Families of metallopeptidases not assigned to clans
6891013681070Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11237Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111111118Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7778777757Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
88161311139987Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
66141391310879Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
4655556541Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1819182419192118156Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2244322322Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
3342414223Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
44497110559494333453Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2288243130Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3344335429Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1122122112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2244231220Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111118
131210131112101495
11
2114
11
123