Peptidases • Chytriomyces hyalinus JEL632 v1.0
Annotations/GenomesBatde5Caupr1Chyhya1Chylag1Chytri1Clapol1_1Enthel1Gaesem1Glopol1Hompol1Obemuc1Rhihy1Spipu1TotalAnnotation Description
Merops
3141523623123553752102073721843303602103,743
103720102733144271315278308Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
24255132233234Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19152720271914151717202215247Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
32466144457106374Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21443232234232Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
11114Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5276666475811477Families of peptidase inhibitors not assigned to clans
22
11
21115
11
11233111111218
123
11114
1112111111112Families of metallopeptidases not assigned to clans
35154546351410224913462511366Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
12734133156238Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2221321121118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
22524234355441Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
741179978778119104Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
11925132533791812272512226Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
421181182452129583Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1121211111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
643546447765465Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112211210Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
9221332811353Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
15183021272417171916201919262Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
535476434369564Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
13111112112Serine or threonine nucleophile; N-terminal nucleophile
22102942158515810110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
4425836710010664418844809849889Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
17658132611213184Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
549576565355772Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
112231113322224Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
323231475145444Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
12122111112
24222629232820212419153115297
126110