Peptidases • Suillus brevipes Sb2 v2.0
Annotations/GenomesBoled1Paxru1Pisti1Rhisa1Rhivi1Suibr1Suibr2Suigr1Suihi1Suilu3TotalAnnotation Description
Merops
5053064974225123714004273,440
6138626460537349460Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1212112212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2015191614161413127Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
103106778758Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4222121115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
54155Water nucleophile; water bound by Gln and Glu; all endopeptidases
111222223236Families of peptidase inhibitors not assigned to clans
123
2223222116
2222222216Families of metallopeptidases not assigned to clans
2415311212121211129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2111121110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
123Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11101198710874Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1616161816141616128Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
149181318131413112Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
213Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5655558544Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
111115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1920212121192220163Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5365565641Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
125138888769Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
90678610794799784704Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6152121119Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4458546440Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
4223343324Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
12164169106218108861661,038
11