Peptidases • Vuilleminia comedens VcCUCC2015_SSI3 v1.0
Annotations/GenomesCylto1Denbi1Phlbr1Phlcen1Punst1Schpa1Vuico1Vuicom1TotalAnnotation Description
Merops
3376994503203903304864883,500
1861655649325860399Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2322113317Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1337181216192319157Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
813177476971Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
7115528Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
1111812Water nucleophile; water bound by Gln and Glu; all endopeptidases
410157333348Families of peptidase inhibitors not assigned to clans
112
1111116
21682354343
3311242218Families of metallopeptidases not assigned to clans
3220201115122221153Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1252111114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1311121111Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1112117810101180Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2243151319122724175Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
123211111191514115Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6765666648Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
2133232121222223186Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
82269678975Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
513311012132129134Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1352611601211451271941871,330Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6198484121475Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
2632334427Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
611112113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3441334426Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
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