Peptidases • Mucoromycotina
Annotations/GenomesAbsrep1Amyrou1Bacci1Benpoi1Blatri1Blatri_F921_1Blatri_F986_2Chlpad1Chocucu1Cirumb1Cokrec1Cunech1Dicele1Dicrob1Ellano1Endsp1Fenlin1Gilper1Gonbut1Halrad1Helpul1Hesve2finisherSCJimfl_AD_1Jimfl_GMNB39_1Jimlac1Kircor1Liccor1Lichy1Mucci2Muccir1_3Mucmuc1Mycafr1Parpar1Phaart1Phybl2Phybla1Pilano1Pilumb1PnitS607_1PnitS608_1PnitS609_1Radspe1Rhich1Rhimi1_1Rhimi_ATCC11559_1Rhimi_ATCC52814_1Rhior3Sakvas1Spifus1Spoumb1Synrac1Thaele1Umbelo1Umbisa1Umbra1Umbsp_AD052_1Zycmex1Zyghet1TotalAnnotation Description
Merops
34230242225225125425731625832724731828830928522733726426725827928328528230736730531130428030123326532328427626124026727427726437625323823229023922925528329429027427227733430216,487
263031201819182324232122242523113424242221261314123626252422251619242831191630323219352020203313193220232422222324311,353Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
43104333432333333233476544463446332444345535434433444323344219Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
112Water nucleophile; water bound by two Asp
353440302626263327282234272832203226282730273127323632353530312330312928302825282731452930282827232431342524242434311,698Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
676555565667677145644641211186456656567856771058646455566222255350Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2162323133222212311332131122222333422221322122124332312130Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
12111111112212111111211221111111111112111123221161Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
322112112122121212121221121212211211121221211270Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
9119735483775777466657547598777837665764446127771354567666687370Families of peptidase inhibitors not assigned to clans
1113
111121131111112111111126
1111121111111121111122
1111116
111211222131112321131122222145
11
89101111131155
22112222221211312211211112121111122222112211311111176
315222222411332242222211533232234113311131111221142331344128
111111111111111111111111111111111111112111111111111153Families of metallopeptidases not assigned to clans
171926182322221728171714192923142017121319121720211916162321231520161715201917151717281815151817141815261615222018241,081Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
3132222217Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
13311133711114112212242Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4444444344434443443343523445445445334433338444433444333346221Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
151315101110101211119111312128141210111411101010129111313101212121213121213131312161411121391291112101011101212673Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1716169777148178131216111415813121011161618151917111111910201513108131213101411111016611121410161617162412744Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
135116555955598786678126876108771287776987687855654456687129101256419Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1112111111211121111111111311221111111111112111111121111266Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
76744444454555425525536377336554555555444410656645436342355271Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
513221522241242312233632112232112211122111111112443331115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
333235201817183017252121182224131916222320212324233620202324191921211718191918182019311719193220192320202019181924251,251Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
44434432324712352323235531035335333334345425322342224323324195Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1111111111111111117Serine or threonine nucleophile; N-terminal nucleophile
1217227151820191528915141410725111091171216141214151092181119191971116151515151188181591111111171081814778Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
855996565051487546936084667762689351746670807574729277826763664961865556574856565659704652485356505776677978717394693,856Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11111131111323221143112115212111121124165Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4374444335354344544364234574546574447355447655243437333348252Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
314Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21212211121121211111123121134121332111111111211111112232185Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
951151246355108561968549222876767649775646659654486475454565326Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
21311111121111111122Families of peptidases of unknown catalytic mechanism not assigned to clans
1121111211111111111111123211111111111111211111111111160
212026222221202019211825282520131920152019232120242420232417222520192620182023232327242420172317202123201817171421151,207
11
1112212131111112123
11
1111116