Peptidases • Dekkera bruxellensis CBS 2499 v2.0
Annotations/GenomesCanar1Canca1Cante1Dekbr2Hanpo2Lipst1_1Nadfu1Picme2Picst3Sacce1Spapa3Wican1TotalAnnotation Description
Merops
1411481511431512001591341481371571821,851
124106510661281812109Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
12111111110Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
121613151422161312151418180Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
21233232323430Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1112218Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213Water nucleophile; water bound by Gln and Glu; all endopeptidases
32434352424440Families of peptidase inhibitors not assigned to clans
11
11
11114
1121121110
22222322232428
11212111111Families of metallopeptidases not assigned to clans
896661076979689Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22112251111120Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
68778778557681Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10131414131015111091019148Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
63799547343666Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
44443445323343Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
162018181819201917201719221Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
32313433282337Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111111110Serine or threonine nucleophile; N-terminal nucleophile
363336433310451Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
302934273360242435252844393Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1311219Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333343233336Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
123Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
32242552223436Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2215Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111112
610911913148891010117
112
1126212
1113