Peptidases • Panaeolus papilionaceus CIRM-BRFM 715 v1.0
Annotations/GenomesAgrped1Bolvit1Corgl3Crevar1Galma1Gymch1Gymjun1Hebcy2Hypsu1Panpap1Phoaln1Phocon1TotalAnnotation Description
Merops
4543353123563883863462863793993833584,382
421934172750291638151939345Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2111111211113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
211320152020151717122018208Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
118751071069410693Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2351311213123Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1211218Water nucleophile; water bound by Gln and Glu; all endopeptidases
343119355533458Families of peptidase inhibitors not assigned to clans
2114
11
122222112
964634456106669
23222221232225Families of metallopeptidases not assigned to clans
463810372820152424443222340Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11131111161119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11311111111114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
10999119108912910115Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
202910151513121517202114201Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1111129121010111210119128Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11211111111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
21126Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55556565556563Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
222419202224212120202319255Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
187811106871213712119Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
151515202214131620251417206Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
165111104127142144138911411551551331,606Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
108491112126812712111Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33344334334340Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
213Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111111111112Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
43444434444345Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111111111112
211324111822181313131311190
22