Peptidases • Phaeoacremonium aleophilum UCRPA7
Annotations/GenomesBotdo1Fusox1Maggr1Necha2Neucr2Phaal1Thite2Trire2Verda1TotalAnnotation Description
Merops
3375472423582562863062,332
18201920261513131Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1214Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
295433228Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
15221624152117130Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
333433221Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2111117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
13244620Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
433455327Families of peptidase inhibitors not assigned to clans
11
22322213
621441321
22
352311116Families of metallopeptidases not assigned to clans
2320121991119113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
452323827Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
212211211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
81310988763Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
19351423111826146Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
6281021913996Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
22Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
344344426Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
3511212Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21262325202325163Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4142734337Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
12148Serine or threonine nucleophile; N-terminal nucleophile
2114Families of serine peptidases not assigned to clans
201982591413108Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
120239711068692110824Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3315776564Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
332232318Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
123Serine nucleophile; catalytic residues in the order Ser, Glu, His
334223320Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
712212Families of peptidases of unknown catalytic mechanism not assigned to clans
11211118
1113131514151394
11
87142224