Peptidases • Cantharellus anzutake C23 v1.0
Annotations/GenomesBotbo1Cananz1CerAGIClaPMI390Hydru2Rhiso1Tulca1TotalAnnotation Description
Merops
3743484554302774273532,664
48303244294144268Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
4414114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19142220182117131Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1121634121260Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
44614524Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
3710Water nucleophile; water bound by Gln and Glu; all endopeptidases
632552225Families of peptidase inhibitors not assigned to clans
94215
11
1113
2312210
525236124
243233219Families of metallopeptidases not assigned to clans
21225314154119185Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111216Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111217Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1214Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
779988957Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
20131914172912124Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11810138141074Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1211117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
566657641Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
23262325372221177Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5588511749Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
2955331912338189Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1021091421596712577781Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12174538Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
345333526Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
542333626Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
145Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
17153847162370226
112
11
1113
12216