Peptidases • Dentipellis sp. KUC8613 v1.0
Annotations/GenomesAurvu1Clapy1Densp1Hetan2Lopni1Ricme1Stehi1TotalAnnotation Description
Merops
3883724003044184404142,736
56378434425136340Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11112129Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
16122118252424140Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
875715101062Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112534117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
8477632Water nucleophile; water bound by Gln and Glu; all endopeptidases
232233318Families of peptidase inhibitors not assigned to clans
11
112
11111128
774445839
222311718Families of metallopeptidases not assigned to clans
22181313151912112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111116Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
778912111468Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
14161313222527130Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
99101413131583Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
12111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
755565639Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
25202022212421153Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
8744811547Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Serine or threonine nucleophile; N-terminal nucleophile
36324219181719183Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
12114612696157162146954Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2732771038Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
443334324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
358523430Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
19141616222323133
1113
224