Peptidases • Mucor circinelloides MU402 v1.0
Annotations/GenomesCokrec1Helpul1Kircor1Mucci2Muccir1_3Parpar1Pilano1Thaele1Zyghet1TotalAnnotation Description
Merops
2472793673042802652612943022,599
212136242219192331216Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
37444344437Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
223036353030303431278Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
66666556551Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
23322244224Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
21111111110Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
22212122216Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
77977777765Families of peptidase inhibitors not assigned to clans
111115
21115
1113
11
11112111110
12523332425
111111118Families of metallopeptidases not assigned to clans
171919232120202624189Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
44444444638Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
91412131312121212109Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8101511111010101297Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
568128777666Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
21322112216Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
45765556548Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
22311322117Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212036232421192025209Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
421033344437Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
91112109117111494Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
607092676361576769606Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1211112110Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
36554777852Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11134111114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
54876455549Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1311111110
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11
11
11