Peptidases • Penicillium solitum IBT 29525
Annotations/GenomesPenbr2Penca1Pench1Pendi1Penex1Penfe1Penja1Penla1Penra1Pensol1Penth1TotalAnnotation Description
Merops
3313812952253703933592963273653183,660
89991111117101413112Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11112219Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
86749811678781Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3740332834353936323634384Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3223335233332Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111211111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
4343365434342Water nucleophile; water bound by Gln and Glu; all endopeptidases
5454455554450Families of peptidase inhibitors not assigned to clans
11
111115
11
111115
11
253331342430
2232132112322
51033787563259Families of metallopeptidases not assigned to clans
11141081310108111511121Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111112213Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
810988778991194Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3030251933302232293023303Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10121161517137101311125Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
4542453433340Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111119Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
222213115120Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1823201818212121191922220Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6985139108118996Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111112210Serine or threonine nucleophile; N-terminal nucleophile
7975777575773Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1091339267132160128961071301021,256Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1514104118131291213121Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4552533353341Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222223222223Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
2211221222219Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
211121333219Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
1515108149131011910124
11
112116
111115
34333103254141