Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Penicillium subrubescens FBCC1632 / CBS132785
Annotations/GenomesPenbi1Penbr2PenbrAgRF18_1Penca1Pench1PenchWisc1_1Pendi1Penex1Penfe1Pengl1Penja1Penla1Penox1Penra1Pensub1Penth1TotalAnnotation Description
Merops
4453313413812953172253703934143592962563274253185,493
168109920911111211711101213179Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11111218Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
7876794981011647107120Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
41373940333528343541393633324334580Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
333223333252333346Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111111111111115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111121111111117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
644343336654235364Water nucleophile; water bound by Gln and Glu; all endopeptidases
655454445555555476Families of peptidase inhibitors not assigned to clans
11
21111111110
112
21111118
22453233213141440
22223321322112331
9571033378575868296Families of metallopeptidases not assigned to clans
15119141010813101410813112211189Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111111111217Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
118710910887778591011135Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
32303130252819333029223219292823440Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10101312111161517111376101511178Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
544543245434233358Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111111111114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
212122123112121Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
20181923202218182119212118191922318Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1066988513911108811129143Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11111111121214Serine or threonine nucleophile; N-terminal nucleophile
7789765779757797114Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
19310911013392956713216017412896761071731021,947Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9151614109411891312691013168Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
445555253433353362Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
222222222232222233Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
322211122212221228Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22211112143232229Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111111116
16151515101381491213108111310192
1112117
1111116
3334323310632253156