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Peptidases • Leucoagaricus gongylophorus AB2 v1.0
Annotations/GenomesAgabi_varbisH97_2Agabi_varbur_1Copci1Leugo1_1Leugon1Macfu1PleosPC15_2Schco3TotalAnnotation Description
Merops
2872852871612533363473452,301
2425111214222429161Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
221221212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
55Water nucleophile; water bound by two Asp
1815151320181820137Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3454369539Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2133211Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
4571292232Families of peptidase inhibitors not assigned to clans
77
112
1225
4354266737
2231323319Families of metallopeptidases not assigned to clans
191830932273222189Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111128Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2212111212Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
997471091065Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1817221414171723142Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101083710101270Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
145Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6672666544Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
2211118Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1818191721202022155Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
111083778761Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111116Serine or threonine nucleophile; N-terminal nucleophile
668971012664Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
98101994476115127132792Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
23243317Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3321443323Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3331344425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111118
1515101114152312115
11