Peptidases • Mortierella elongata MPI-CAGE-AA-0104 v1.0
Annotations/GenomesLobtra1MorGBAus27b_1Morel2Morel_U14_1Morhum1Mormul1Morve1TotalAnnotation Description
Merops
2942864053503112733222,241
17133631231725162Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
555535533Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
29252529252427184Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
667765542Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11312210Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
778879753Families of peptidase inhibitors not assigned to clans
11215
1111116
112
331213215
111131210
421211112Families of metallopeptidases not assigned to clans
20182835201723161Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
334555530Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
232233217Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
333333321Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1011101212111278Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
171413139121593Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
667766644Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
333313218Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1321119Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19182019191820133Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
666563638Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11Serine or threonine nucleophile; N-terminal nucleophile
1438Families of serine peptidases not assigned to clans
17241916291724146Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
72719586665775522Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
951820241022108Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
555454533Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
444234122Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
18237019172614187
1113