Peptidases • Ustilaginomycotina
Annotations/GenomesAcain1Cersp1Exomac1Exova1Hethyg1Jamsp1Malgl1Malsy1_1Meimi1Melen1Moeaph1Monili2Psean1_1Psehu1Rhanym2_1Rhodsp1Spore1Tescy1Tilalb1Tilan2Tillet1Tilwa1Uroocc1Uropr1Ustgig1Usthor1Ustma2_2Ustsp1TotalAnnotation Description
Merops
2171692582061811661381101971851432221491501551691561591901562431601621451541681581674,833
9711139111761021811851110761181868873487295Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
113221112211111111212111111136Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1113Water nucleophile; water bound by two Asp
1610191414151391811112614151016131412101511201316151710397Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
222222222218122322222222222261Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2342321331112132311112144Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
223322223233222323222322222264Families of peptidase inhibitors not assigned to clans
111115
1111111111111211111111124
24331131211111131111134
22212311121211131213212122346Families of metallopeptidases not assigned to clans
881561177596777587798799765678211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111111111111111122Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
311117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111111111111111111111122Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6495456555585345555564465556145Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
111113898767999999711810710117898713250Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
94535322564744454511563444446132Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
5565544455555444555665456556138Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19192520211817141920182418171818201920182020191919192018536Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4253343283554324443345454334106Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111211119Serine or threonine nucleophile; N-terminal nucleophile
649956241421522442227243212223140Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
916491745956293064544753515550555051694585495740514251541,567Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
242221212223122612112245Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
22621233321412211231312111255Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
21332322221211213231112221149Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111112111111111111111128
108121310914101110715671078911139981088810270
123
1113
2214415223424214123213257