Peptidases • Microthyrium microscopicum CBS 115976 v1.0
Annotations/GenomesAplpr1Aulhe2Erebi1Leppa1Micmi1Patat1Phycit1Sacpr1Totfu1Tryvi1TotalAnnotation Description
Merops
2943142703483902592552903883563,164
25201217341115292619208Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
563542365342Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
112Water nucleophile; water bound by two Asp
22222329232522262826246Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
233532232429Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
232213222120Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12211119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
311112231419Water nucleophile; water bound by Gln and Glu; all endopeptidases
554545545547Families of peptidase inhibitors not assigned to clans
11
11
112
121111122113
31746627
5137532311040Families of metallopeptidases not assigned to clans
911121421171282212138Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
222413113221Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
222422222121Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
567886666866Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
20282020221718212415205Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10981488101091298Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
334333333331Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
231213112218Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
24221720212320212324215Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
324562434336Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11112111110Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
10159151467122226136Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
99117951101527887981521381,126Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
93681223313665Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
443333331330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
212232221118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
433335433334Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1111163012141091111135
11
11
113381325330