Peptidases • Aspergillus tubingensis v1.0
Annotations/GenomesAspac1Aspbr1Aspca3Aspfo1Aspni5Aspnid1Aspsy1Asptu1Aspve1Aspwe1Eurhe1Pench1TotalAnnotation Description
Merops
3583994093722914073734283642442953,940
13161712461261889121Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1434113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
10781033281033777160Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3133383510203319383133321Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3333333323231Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
111115Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
6566436233448Water nucleophile; water bound by Gln and Glu; all endopeptidases
5555545496558Families of peptidase inhibitors not assigned to clans
11215
1113
11
11
11
1111321321319
644445331337
10106979101357389Families of metallopeptidases not assigned to clans
1014181416221519191210169Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111111110Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
89118568764981Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2827242540382541251625314Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1120141681215168811139Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4545125233438Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1121117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
224412Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2219232017191819202020217Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
56117469997881Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1212118Serine or threonine nucleophile; N-terminal nucleophile
10111111459496787Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1381681661496114015014112670921,401Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6106416781011069Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4323153554540Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222232321223Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111216Serine nucleophile; catalytic residues in the order Ser, Glu, His
2131211112116Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2233322118Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111
91013108101010111210113
1225
112
1113
3213833381073135