Peptidases • Bimuria novae-zelandiae CBS 107.79 v1.0
Annotations/GenomesBimnz1Bysci1Karrh1Lenfl1Maseb1Stasp1Trepe1Veren1TotalAnnotation Description
Merops
4143934224283394544163553,221
1513172112162218134Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
87866127761Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2927323129322829237Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4546445436Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1112311111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
2233222117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3212311114Water nucleophile; water bound by Gln and Glu; all endopeptidases
5554545538Families of peptidase inhibitors not assigned to clans
11
111111118
9376566648
10788565554Families of metallopeptidases not assigned to clans
1622171617201814140Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
6556473440Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2221112112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
7985856856Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2727292626292518207Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1311913141314996Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3333333324Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
4444432227Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2423232121222021175Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
11911109128777Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111111118Serine or threonine nucleophile; N-terminal nucleophile
2216191311131112117Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1521501601721151941701371,250Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
614161741314791Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333333324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111121210Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3344555433Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
1716141511121617118
11114
11
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