Peptidases • Absidia repens NRRL 1336 v1.0
Annotations/GenomesAbsrep1Bacci1Lichy1Morel2Mucci2Phybl2Rhimi1_1Umbra1TotalAnnotation Description
Merops
3424223114053042842532722,593
2631253624282022212Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
41035444337Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3540352535292924252Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6657676245Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21613232231Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1121128Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
221121110Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
9978767659Families of peptidase inhibitors not assigned to clans
112
111115
112
11
2125
2111112110
3531211117
111111118Families of metallopeptidases not assigned to clans
1726162823171822167Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
426Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
132118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4453434330Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1515111013121411101Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1716171311151117117Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
13117712961075Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11112118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
7733656239Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
5323111319Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3335202023171718183Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4456333331Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
1222151910191110118Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8596829567554671597Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
131811125Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4745546338Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2211331215Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
91164776454Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2114Families of peptidases of unknown catalytic mechanism not assigned to clans
121111119
2126237024262417231
11114
11
11