Peptidases • Phlebia centrifuga FBCC195
Annotations/GenomesCylto1Denbi1Phlbr1Phlcen1Punst1Schpa1TotalAnnotation Description
Merops
3376994503203903302,526
186165564932281Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
23221111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
133718121619115Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
8131774756Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
718Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
1113Water nucleophile; water bound by Gln and Glu; all endopeptidases
4101573342Families of peptidase inhibitors not assigned to clans
11
11114
216823536
33112414Families of metallopeptidases not assigned to clans
322020111512110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12521112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1311129Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
111211781059Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
224315131912124Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1232111111986Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
67656636Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
213323212122141Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
822696758Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
5133110121384Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
135261160121145127949Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
619848449Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
26323319Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
6111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
34413318Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116
96414134820168
11
11
11