Peptidases • Crucibulum laeve CBS 166.37 v1.0
Annotations/GenomesCorgl3Crula1Galma1Hypsu1Lacam2Trima3TotalAnnotation Description
Merops
3123643883793242762,043
342727383029185Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1112229Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201520171614102Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
791094443Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
31123818Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
224Water nucleophile; water bound by Gln and Glu; all endopeptidases
369510336Families of peptidase inhibitors not assigned to clans
11819
1225
44363323
23223214Families of metallopeptidases not assigned to clans
102628241817123Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111149Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
31113110Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9911911857Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10201517101486Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1214121281270Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
55655632Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191922202127128Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
89101212455Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1124Serine or threonine nucleophile; N-terminal nucleophile
1513222010585Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1041411421417877683Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
461185135Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
34433320Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
45444425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
241818133720130
11