Peptidases • Aspergillus japonicus CBS 114.51 v1.0
Annotations/GenomesAspfu1Aspjap1Aspni7Aspnid1Aspor1TotalAnnotation Description
Merops
2743513882914141,718
4131541349Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11428Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
16833654Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
5034341034162Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3433316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11125Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
2754321Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
7555426Families of peptidase inhibitors not assigned to clans
11
11
11
21137
274114
11
1311771452Families of metallopeptidases not assigned to clans
131214162580Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11125Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
4785731Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1726264026135Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
791781354Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3551115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
2136Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2021201726104Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6484931Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
123Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
89124942Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
5913416061153567Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
17101726Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3431718Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
5122313Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
121217Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2133918Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
1110981957
11
112
18338362