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Peptidases • Thanatephorus cucumeris MPI-SDFR-AT-0096 v1.0
Annotations/GenomesBotbo1Cananz1CerAGIClaPMI390Hydru2Rhiso1Thacu1Tulca1TotalAnnotation Description
Merops
3743484554302774274063533,070
4830324429412744295Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
44144118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1914222018211917150Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
112163412131273Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
446142526Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
3710Water nucleophile; water bound by Gln and Glu; all endopeptidases
6325522227Families of peptidase inhibitors not assigned to clans
942116
11
1113
23121211
5252367131
2432333222Families of metallopeptidases not assigned to clans
2122531415413919224Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1112319Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11112118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1214Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7799889966Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2013191417292112145Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1181013814101084Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
12111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5666575646Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2326232537222321200Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
55885119758Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
295533191233298218Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1021091421596712513277913Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12174538Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3453336532Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
5423334630Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
145Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1715384716233070256
1113
112
1113
12216