Peptidases • Psilocybe cubensis v1.0
Annotations/GenomesAgrped1Galma1Gymch1Gymjun1Hebcy2Phoaln1Psicub1_1TotalAnnotation Description
Merops
4543883863462863833722,615
42275029161928211Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
21111118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
21202015172016129Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1110710610862Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213113213Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
121116Water nucleophile; water bound by Gln and Glu; all endopeptidases
393553432Families of peptidase inhibitors not assigned to clans
21115
11
12216
934456637
222212213Families of metallopeptidases not assigned to clans
46282015243230195Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111117Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11111117Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
101191089966Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
20151312152121117Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1112101011111075Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1124Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
565656538Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
22222421212319152Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
181068771470Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
15221413161416110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
16514214413891155143978Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1011121267967Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
343344425Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
444344326Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111117
21182218131311116
22