Annotations/Genomes | Total | Annotation Description | ||||||
---|---|---|---|---|---|---|---|---|
![]() Merops | 304 | 338 | 286 | 266 | 1,194 | |||
34 | 32 | 10 | 10 | 86 | Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms | |||
1 | 1 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane. | ||||||
1 | 2 | 5 | 3 | 11 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane. | |||
18 | 29 | 25 | 27 | 99 | Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence | |||
7 | 9 | 3 | 3 | 22 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | |||
5 | 1 | 3 | 2 | 11 | Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence | |||
1 | 1 | 2 | Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence | |||||
1 | 1 | Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence | ||||||
1 | 1 | 2 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | |||||
2 | 2 | 4 | Water nucleophile; water bound by Gln and Glu; all endopeptidases | |||||
2 | 11 | 4 | 4 | 21 | Families of peptidase inhibitors not assigned to clans | |||
18 | 18 | |||||||
1 | 2 | 1 | 1 | 5 | ||||
4 | 2 | 3 | 2 | 11 | ||||
3 | 3 | 1 | 1 | 8 | Families of metallopeptidases not assigned to clans | |||
13 | 17 | 18 | 14 | 62 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp | |||
1 | 3 | 3 | 7 | Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His | ||||
1 | 4 | 1 | 1 | 7 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu | |||
1 | 4 | 5 | Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu | |||||
9 | 12 | 10 | 10 | 41 | Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu | |||
13 | 16 | 19 | 20 | 68 | Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His | |||
14 | 9 | 9 | 9 | 41 | Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His. | |||
1 | 1 | 2 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site. | |||||
5 | 9 | 3 | 3 | 20 | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D) | |||
1 | 1 | 2 | Water nucleophile; water bound by single zinc ion ligated to Asp, His and His. | |||||
1 | 1 | 2 | Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases | |||||
22 | 23 | 21 | 21 | 87 | Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme | |||
4 | 12 | 2 | 4 | 22 | Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence. | |||
1 | 1 | 1 | 3 | Serine or threonine nucleophile; N-terminal nucleophile | ||||
19 | 10 | 11 | 9 | 49 | Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs | |||
96 | 74 | 97 | 87 | 354 | Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence | |||
2 | 2 | 6 | 3 | 13 | Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence | |||
3 | 4 | 3 | 3 | 13 | Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence | |||
1 | 1 | Serine nucleophile; catalytic residues in the order Ser, Lys in sequence | ||||||
1 | 1 | 3 | 3 | 8 | Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence | |||
1 | 1 | Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS. | ||||||
5 | 6 | 4 | 3 | 18 | Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane | |||
1 | 1 | Families of peptidases of unknown catalytic mechanism not assigned to clans | ||||||
1 | 1 | 1 | 1 | 4 | ||||
16 | 21 | 11 | 9 | 57 | ||||
1 | 1 | |||||||
1 | 2 | 3 |