Peptidases • Leotiomycetes sp. MPI-SDFR-AT-0126 v1.0
Annotations/GenomesCadsp1Greab1Leptod1Marbr1Phimu1TotalAnnotation Description
Merops
7253266572465672,521
3117331028119Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1791781869Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3724342330148Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3443317Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
114129Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
5111311Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1124Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
4352418Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5554423Families of peptidase inhibitors not assigned to clans
112
213
11226
7343421
112
104102531Families of metallopeptidases not assigned to clans
3310281622109Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2222210Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111216Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1191041044Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
4124401837160Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
2582391984Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4433418Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
7153218Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2723252124120Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1321331142Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
21115Serine or threonine nucleophile; N-terminal nucleophile
4018421230142Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
315119283692551,041Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3052621679Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3332314Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
121116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3234214Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
121127Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
301317111485
2114
415212