Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Mariannaea sp. PMI_226 v1.0
Annotations/GenomesAcrst1Beaba1Cloro1Cormi1Ilyrob1MarPMI226Metan1Myrin1Necha2Nieex1Trire2Valla1TotalAnnotation Description
Merops
4813657023216223214395474822862034,769
172216242314172025159202Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1311121111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
921031213943258Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1922231829201722292118238Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3424533333336Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1112121211114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
17410411386146Water nucleophile; water bound by Gln and Glu; all endopeptidases
4352423345338Families of peptidase inhibitors not assigned to clans
1214
112
11
21221222115
1211112251118
23218
32831048571152Families of metallopeptidases not assigned to clans
2226381927202120241110238Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1431236214533267Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2211322121219Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
10713118910131088107Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3620502033143535241811296Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
2714361228181828271311232Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4444444444444Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
51222751254164Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2321262225232426242320257Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
75124141181464287Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2434343234133Serine or threonine nucleophile; N-terminal nucleophile
112Families of serine peptidases not assigned to clans
22324327248261918148241Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2111043048128011817623920792591,871Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
101622153612731176172Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3343233332332Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111111111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
3323333323331Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112116Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
91215812111513101510130
1214
11
11
23101522712439