Peptidases • Aspergillus niger (phoenicis Corda) Thom ATCC 13157 v1.0
Annotations/GenomesAspni7Aspni_NRRL3_1Aspni_bvT_1Aspnid1Aspph1TotalAnnotation Description
Merops
3884043822913751,840
15151541564Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
44Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
89733764Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3437351033149Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3433316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
5554524Water nucleophile; water bound by Gln and Glu; all endopeptidases
5555525Families of peptidase inhibitors not assigned to clans
11
11
111317
444517
7777735Families of metallopeptidases not assigned to clans
141514161574Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
81075838Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2628304029153Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
17161581571Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
5551521Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
202020171996Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
8994939Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11Serine or threonine nucleophile; N-terminal nucleophile
12131241354Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
16016415561153693Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
101191738Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3221210Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222210Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
121217Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3223212Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
910108845
11
11
3838