Peptidases • Neocallimastigomycetes
Annotations/GenomesAnasp1Caecom1Neosp1Orpsp1_1PirE2_1Pirfi3TotalAnnotation Description
Merops
3314574434953952282,349
122247137Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
22412213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
181930421620145Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1192110131478Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
13116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
213Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1242466557Families of peptidase inhibitors not assigned to clans
1311413313156
11
11114
112116
112
11
11688437Families of metallopeptidases not assigned to clans
4851451166630356Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11226Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to His, Asp and His
21142111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
34554324Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
571086541Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
861576547Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
13131110Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
55745531Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
284115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
151731171517112Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
12391319Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111216Serine or threonine nucleophile; N-terminal nucleophile
432016423817176Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9114412511812758663Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
123Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
63822324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
22Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
10101564550Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
21412212
151633503415163
11
2125
224