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Peptidases • Mytilinidiaceae sp. NC0267 v1.0
Annotations/GenomesHyspu1_1Leppa1Lophiu1Lopmy1Mytre1Polfu1Rhyru1_1TotalAnnotation Description
Merops
3333483783794014363512,626
11171620202015119Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
55981110856Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
29293333282822202Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
353334324Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
222321113Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
322222417Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
313351218Water nucleophile; water bound by Gln and Glu; all endopeptidases
355655534Families of peptidase inhibitors not assigned to clans
11
11
1111116
413534424
275763434Families of metallopeptidases not assigned to clans
12141214172219110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
343325424Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
242222216Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
781110107558Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
15202628282620163Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10141418141518103Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
233333219Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
221131212Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19202121222322148Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5574610744Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11211118Serine or threonine nucleophile; N-terminal nucleophile
13151171212979Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
136110146143146183133997Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1588612171480Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
233333219Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22423114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
433235222Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111117
11301214201211110
1111116
1111116
233233420