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Peptidases • Leucoagaricus gongylophorus AS2 v1.0
Annotations/GenomesAgabi_varbisH97_2Agabi_varbur_1Leugo1_1Leugon1LeugonAS2_1Lycper1Macfu1TotalAnnotation Description
Merops
2872851612533243503361,996
24251214161722130Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
221243216Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
18151320251918128Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
344355630Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2136Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
4512316940Families of peptidase inhibitors not assigned to clans
77
1113
224
434258632
221332215Families of metallopeptidases not assigned to clans
1918932293027164Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111218Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
222121111Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9947971055Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
18171414161817114Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1010379111060Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
44Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6626106642Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
221112110Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18181721222020136Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
11103799756Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11112118Serine or threonine nucleophile; N-terminal nucleophile
669716121066Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
981014476106129115669Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
235414Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
331431419Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1112117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
331334421Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11111117
15151114171515102