Peptidases • Stereum hirsutum FP-91666 SS1 v1.0
Annotations/GenomesCersu1Copci1Cryne_H99_1Hetan2Phchr1Pospl1Pucgr1Schco1SerlaS7_3_2Serla_S7_9Stehi1Ustma1TotalAnnotation Description
Merops
3402871573041963624141482,208
41116342081368237Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111012Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
11121219Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
516Water nucleophile; water bound by two Asp
131514188192418129Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
75376410244Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
15121111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
66Water nucleophile; water bound by Gln and Glu; all endopeptidases
2722223222Families of peptidase inhibitors not assigned to clans
11
112
111227
352421825
2313427224Families of metallopeptidases not assigned to clans
9308131115127105Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
211116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111115Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
97894814463Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13221313315276112Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
118101481715487Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1113Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6755156540Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1124Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
171917228202118142Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6834345134Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
24811910919292Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1369940967510114650743Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2225410328Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3233633124Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
333545427Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
211010161120236117
112
123