Peptidases • Hyalopycnis blepharistoma ATCC 48560 v1.0
Annotations/GenomesAgahy1Chiap1Croqu1Eryha1Hetpy1Hyabl1Melli1Mellp1Mixos1Pucgr1Pucst1Rhoba1_1Rhomi1Rhosp1Sporo1Trisp1TotalAnnotation Description
Merops
1781971922321721811782421832241851871651581742,848
1119271312123925301410149117253Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
21151111122322126Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201819182221143011222013151617276Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33223333232322238Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1421221114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111111111Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33322223223223337Families of peptidase inhibitors not assigned to clans
111115
112
111115
23232237133121136
111111111111113Families of metallopeptidases not assigned to clans
109566810971110971016133Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
211111121213Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111339Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111122111116Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
66667747477677592Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
81071488486141113995134Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
565116657591081085106Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
65564677457555582Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191723191819171717261820171817282Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
32122212322223130Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
2473335681612121376Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
465354864449437760524756423343785Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
216223241528Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33343332225334447Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21112112121217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
34242211414432239Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111111111113
1214111213129179181112141411189
213
11
1135