Peptidases • Polyporus arcularius v1.0
Annotations/GenomesDicsq1Gansp1Laesu1Neole1Phchr1Polar1PosplRSB12_1Trave1TotalAnnotation Description
Merops
4073803333204433344332,650
44483939524762331Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
122222112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
16151221141315106Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6522556453Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
311229Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
386241125Water nucleophile; water bound by Gln and Glu; all endopeptidases
2102332224Families of peptidase inhibitors not assigned to clans
11111117
321231214
227335224Families of metallopeptidases not assigned to clans
15141312161422106Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1135Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
8889910961Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13131319161315102Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1511131511111288Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
669657746Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
22222324222022155Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
7644105541Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
32251410302334168Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
136128114116184113178969Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
5314114634Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
442345426Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
545244327Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
52351612271713172
11
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