Peptidases • Cylindrocarpon olidum MPI-CAGE-CH-0241 v1.0
Annotations/GenomesCylol1Daces1Ilyeu1Ilyrob1Ilysp1MarPMI226Neodi1TotalAnnotation Description
Merops
4915726736226773214003,756
21172223231415135Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
6131012121458Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
23252729312018173Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
453543327Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
132111110Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111218Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
324441220Water nucleophile; water bound by Gln and Glu; all endopeptidases
324442322Families of peptidase inhibitors not assigned to clans
322119
1113
222221112
311111412
68810124351Families of metallopeptidases not assigned to clans
33303327292022194Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
455652633Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
223352320Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
698889856Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
27373433361426207Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
23243128331816173Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
454444429Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111116Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
135551323Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
25262425282323174Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
8515141611776Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
223334320Serine or threonine nucleophile; N-terminal nucleophile
2321302425817148Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2072633152803121181631,658Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
22263936371220192Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
233233218Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, Glu, His
434343425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
222221213Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
131218121311988
11
1113
11
285572130