Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Paracoccidioides brasiliensis Pb03
Annotations/GenomesAspnid1Eurhe1Gymau1Monpu1Monru1Parbr1Penex1Theau1TotalAnnotation Description
Merops
2912442242432621373702141,985
4810893111063Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
4116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
33724329767Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1031253334213427215Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3323323322Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1222119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111217Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
43223216Water nucleophile; water bound by Gln and Glu; all endopeptidases
5665524538Families of peptidase inhibitors not assigned to clans
11
112
11
11
11
11
311223113
112311211
772237331Families of metallopeptidases not assigned to clans
1612131075131187Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
12111118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
5467758648Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
401615192173312163Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
8891013515876Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1333334222Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
2125Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1720192020191822155Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
47357213344Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
4669957551Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
61706565743313258558Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11689311342Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
142325219Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2122222114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
222122213Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3126Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
8128912714979
11
11
11114
38733313563