Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Aspergillus creber IBT 32277 v1.0
Annotations/GenomesAspcreb1Aspfu1Aspni_NRRL3_1Aspnid1Aspor1TotalAnnotation Description
Merops
4222744042914141,805
741541343Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
414211Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
341933683Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2050371034151Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3343316Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1124Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
3254317Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
4755425Families of peptidase inhibitors not assigned to clans
11
11
11
22138
324110
11
1513771456Families of metallopeptidases not assigned to clans
201315162589Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11125Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
64105732Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
4117284026152Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1371681357Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
2351112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
52310Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2020201726103Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6694934Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1124Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
48134938Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1375916461153574Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
81111728Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5321718Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
3522315Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
112217Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3223919Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
11111081959
213
11
112
351838394