Peptidases • Eutypa lata UCREL1
Annotations/GenomesBotdo1Eutla1Fusox1Maggr1Necha2Neucr2Thite2Trire2Verda1TotalAnnotation Description
Merops
4473375472422562863062,421
16182019261513127Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11215Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
629533230Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
19152216152117125Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
433333221Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3211119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11211118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
41324620Water nucleophile; water bound by Gln and Glu; all endopeptidases
543355328Families of peptidase inhibitors not assigned to clans
11
22232213
162141318
11
635211119Families of metallopeptidases not assigned to clans
2323201291119117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
345223827Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
221211211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
118131088765Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
31193514111826154Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
28628109139103Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
22Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
434444427Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
3351214Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21212623202325159Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
7414234337Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11248Serine or threonine nucleophile; N-terminal nucleophile
12115Families of serine peptidases not assigned to clans
272019891413110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
175120239718692110893Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12331576569Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333232319Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
433423322Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
71210Families of peptidases of unknown catalytic mechanism not assigned to clans
11121118
1211131314151391
11
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