Peptidases • Umbelopsis sp. PMI_123 v1.0
Annotations/GenomesUmbelo1Umbisa1Umbra1Umbsp_AD052_1TotalAnnotation Description
Merops
2902742722771,113
2422222391Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
323311Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2524242497Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
22228Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
332311Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11114Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
23229Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
666624Families of peptidase inhibitors not assigned to clans
11114
112
11114
22228
1113
331310
11114Families of metallopeptidases not assigned to clans
1615222073Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22228Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22127Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
333312Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1010111041Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1616171665Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
129101243Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
342312Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
443314Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2019181976Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
323311Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11710836Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
79787173301Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
21126Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333312Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
12238Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
454518Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
1817171466
11