Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Pichia pastoris
Annotations/GenomesAscru1Babin1Canar1Canca1Canta1Cante1Cybja1Dekbr2Hanpo2Hanva1_1Hypbu1Lipst1_1Metbi1Nadfu1Pacta1_2Picme2Picpa1Picst3Sacce1Spapa3Wican1TotalAnnotation Description
Merops
1551711411481491511671431511111532001421591521341281481371571823,179
10121241510146561010126106101281812208Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1112111111111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
141712161313161514111522141613131112151418304Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
94212223334223222323460Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1211112121114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111119Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1214Water nucleophile; water bound by Gln and Glu; all endopeptidases
44324443423345424424473Families of peptidase inhibitors not assigned to clans
112
11
111115
1111112111121116
22222232232322222232448
11111211112111111120Families of metallopeptidases not assigned to clans
913896666661110677669796159Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111111111120Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1222111123121512111132Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
676877778667776865576139Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
814101312141914131112101115141181091019257Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
546337799245449733436107Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3244445433434452323369Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191616201818181818161819162018191817201719378Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
232333132423233282354Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111111111117Serine or threonine nucleophile; N-terminal nucleophile
733633533446344333310487Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
314530293334322733213560292429242635252844674Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11131112112116Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43333333333334333233364Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111227Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111115Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
33321234212525423223458Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2215Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111111111120
8761099911979131114989891010195
1113
1121113216221
22
11114