Peptidases • Melanomma pulvis-pyrius v1.0
Annotations/GenomesAltbr1CocheC5_3Dotse1Hyspu1Melpu1Mycgr3Sepmu1TotalAnnotation Description
Merops
2823723194663422862,067
122917202210110Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
712454537Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
192825312725155Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34352320Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11312311Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11215Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111115Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
25345221Water nucleophile; water bound by Gln and Glu; all endopeptidases
45355426Families of peptidase inhibitors not assigned to clans
2111117
53543323
26282121Families of metallopeptidases not assigned to clans
13119272818106Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
87344329Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6687101047Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
162617331719128Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12910126958Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
33434320Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
4233214Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212024222121129Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
109376237Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
123Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
3111118Serine or threonine nucleophile; N-terminal nucleophile
9161022161184Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8713212417711997736Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
657258657Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33323317Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22213313Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
23543421Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
123Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
1515142091184
112
11
3222110