Peptidases • Mortierella
Annotations/GenomesMoeNVP64_1MorAD185_1_1MorGBAus27b_1Moramb1Morcap1Morel2Morel_U14_1Morgam1Morhum1Mormin1_1Mormul1Morve1Morwol1TotalAnnotation Description
Merops
3583672862742494053503613113482733222404,144
35111311133631332326172512286Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
555335553555357Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
28392524212529262528242722343Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
866557766555475Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12121313222121Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
17211214Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111111111112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111115Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
877338897697587Families of peptidase inhibitors not assigned to clans
111123110
1111111119
1113
11
263221231332232
111211113212219
122211221111219Families of metallopeptidases not assigned to clans
38311826262835312035172318346Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
543544565655461Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
223222223232229Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
333333333333339Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
111111991012111213111211143Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1312141311131314912121515166Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
7565577116766583Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111111113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
433333321332336Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
26113221111223Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21201816162019201919182016242Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
556456546536565Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11Serine or threonine nucleophile; N-terminal nucleophile
11141311Families of serine peptidases not assigned to clans
15342420171916202934172415284Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
88647167629586806676577555942Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
205596182025241610225185Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
465555455745565Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
131111111111115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
354534233341242Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111112
19632314127019261717261414334
11114
11