Peptidases • Calocera cornea v1.0
Annotations/GenomesAgabi_varbisH97_2Aurde1Botbo1Calco1Copci1Dacsp1Lacbi2Phchr1PosplRSB12_1Schco2SerlaS7_9_2Treme1Walse1TotalAnnotation Description
Merops
2873743422872993383343461491522,908
244827113032476153288Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
24232211118Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
55Water nucleophile; water bound by two Asp
18192215192913221416187Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3111539644349Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
243121221119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3216Water nucleophile; water bound by Gln and Glu; all endopeptidases
4637311222343Families of peptidase inhibitors not assigned to clans
91827
11
1113
12126
452512111224
222323522124Families of metallopeptidases not assigned to clans
1921930517141196141Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111241112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2111241214Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
979710121088686Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
182023221816131599163Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10111081291115107103Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
654759765357Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
211127Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18232219232320212018207Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
11538312543559Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
629128101023912110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9810212899102741131143140901Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
21215212244154Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
335254533235Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
354336454340Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1517211014211722913159
11
1113
3115