Peptidases • Eurotiomycetes
Annotations/GenomesArtbe1Aspac1Aspacri1Aspacu1Aspalbe1Aspamy1Aspara19utrAspave1Aspber1Aspbisp1Aspbom1Aspbr1Aspbrev1Aspbru1Aspca3Aspcae1Aspcal1Aspcam1Aspcand1Aspcar1Aspchev1Aspcl1Aspcor1Aspcos1Aspcri1Aspdese1Aspegy1Aspell1Aspeuc1Aspfij1Aspfili1Aspfl1Aspfo1Aspfu1Aspfu_A1163_1Aspfuni1Aspgl1Asphet1Asphom1Aspibe1Aspind1Aspind2_1Aspinso1Aspjap1Aspka1_1Asplac1Aspmin1Aspmul1_1Aspne1Aspneo1Aspneoa1Aspni7Aspni_DSM_1Aspni_NRRL3_1Aspni_bvT_1Aspnid1Aspnom1Aspnom13137_1Aspnov1Aspnovo1Aspoch1Aspoch1432_1Aspoli1_1Aspor1Asppar1Aspparv1Asppeni1Aspph1Asppip1Asppsec1Asppsen1Asppset1Aspram1Asprec1_1Aspres1Asprobu1Aspros1Aspsac1Aspsc1Aspscl1Aspscle1Aspser1Aspste1Aspstec1_1Aspstel1_1Aspsy1Asptaic1Asptam1Aspte1Asptr1Asptra1Asptu1Aspuda1Aspund1_1Aspung1Aspuva1Aspvad1Aspve1Aspven1Aspvio1Aspwe1Aspwel1Aspzo1Blade1Bysni1Byssp1Calor1Capcor1Capep1Capse1ClaNC0930_1Claba1Claca1Claim1Claps1Claye1Cocba1Cocim1Cypeu1EndpusZ1Eurhe1EurotioJF033F_1EurotioJF034F_1Exoalc1Exoalc1_J33Exoaq1Exode1Exome1Exool1Exosi1Exosp1Exoxe1Fonmo1Fonmu1Fonnu1Fonpe1Gymau1Gymci1_1Hisca1Micca1Monpu1Monru1Neofi1Paevar1Paevar_HGY_1Parbr1Parbra1Penac1Penant1Penatra1Penbi1Penbr2PenbrAgRF18_1Penca1Pench1PenchWisc1_1Pencop1Pendec1Pendi1Pendig1Penex1Penexp1Penfe1Penfla1Pengl1Pengri1Penita1Penja1Penla1Pennal1Pennord1Penox1Penpol1Penra1Pensol1Pensoli1Penste1Pensub1Penswi1Penth1Penvul1Phach1Phiatt1Talabor1Talma1_2Talpro1Talst1_2Theau1Theau2Thelan1ThyNC0857_1Triru1Triver1Uncre1TotalAnnotation Description
Merops
22335835841139935140947526627336725435836335339837227426827330131735935035135937835838837940438229139432222922241437536321629238339537140732237331535235642834736431423434426124627230436649740531939243431725022038621024439540238237751323730747335442142336340535137122421917424424326230926026213716350533028644533134138129531727019522522637034439328841428124835929628829325629832736535831642538231829423338924734652736421421714930123922719847,657
913141216131797913915151415124481410161413111514151315154137771315136121617136912814136131891111819811162116121816111451012817181191299201315101313131410948897993322101016810992097981181191277117151011710149111210131312121238312410117189951,709Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2111151111111141222213141111111111111223122111111121111211111111122111111221122110Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
31010678828447789751012898108689987973342996781159952851037833678411696412797111584410671211111013581479158118823214338722175578767953449884104711666477810910879377108877662241,131Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
22313334333438232441323431353529355051352631303334373135343337351031511918343333173031344020353349313719343835272824272223243529233128272220261931293125262422253123303024232424252518223334522832212245372741373940333524202829343035304133283936303233283236352743323425222722303331272819322623174,422Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33333333333323333333322343333343333443333233333334334232323233253344325134433326454533332222333332253233322331333333233523333333233322344563333332442Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2221231111212111111121111111212113121112211311113123111111114215111211221111111111111111111111111111111111221111148Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111111111111111111111111111111111111111111111111111111121111111111111111111221111211111111111112111111111111119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
11111111112111111111111111111111111137Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
6645662226476626224778676565455432333563576233636626334724191113111111111111122366102464434321333363643544322344453323691382225488Water nucleophile; water bound by Gln and Glu; all endopeptidases
1113Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
35545556755655555777455555555555546554553555545565545965553565554554445464555545544545456455556552455565545444444454554554553544555433455545555433697Families of peptidase inhibitors not assigned to clans
1111212111113
1111121111111111111121
2111211111211111111111111230
11
111111111111113
2112111111111112120
11
11111212111111122211111111111131111111111221113121111111111121211111111121111111111122211133224532113331232133311422134311112122193
642444513533442422223557446444422211542364142515435321511444463763212212466423636467661212313211722222233122123121221111124123322244572231426
112
410151410146151178669151691313771151211767777771318861478577520914101311913115656432339327522234721324234123243426162315348839571033102337685575753866356892632651333257442932Families of metallopeptidases not assigned to clans
141092314918231315151116131224141313121016161212141513141515141621151115251513121118181222121512141219141913121511109111318111111111210151418121412131216111014814156979131291610717995912915151191410108888131510121499108101113121115101022151111111171212111111691515141,854Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
211211121111112111111111111112111211111121111111111111211225111113131111211211111111111111111111111111111121112221121511111111233163Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111111111111111111311111111111121111211121111112111111111112111111176Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111111111Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
788797116107867897844666787979881075963578857997698678776412888578106786767884777766871079676766577787859101181187109106488897107910781012510991091091188651010765687771,099Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10282826272524391722241822222626251716152024222626223022263428304029