Peptidases • Septoria musiva SO2202 v1.0
Annotations/GenomesAltbr1Bauco1CocheC5_1Dotse1Hyspu1Lepmu1Mycfi2Mycgr3Pyrtr1Pyrtt1Rhyru1Sepmu1Seppo1Settu1Stano2TotalAnnotation Description
Merops
2822953192603443422973052862663243433,663
121317101722132610101613179Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
75446488539770Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
192825222827262425272225298Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33353244334340Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1232211321119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111129Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1112111111112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
22322511223126Water nucleophile; water bound by Gln and Glu; all endopeptidases
44345555445452Families of peptidase inhibitors not assigned to clans
21121122111116
53553335324546
22233223115430Families of metallopeptidases not assigned to clans
1399111728141118141216172Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
8362476337756Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12111121111114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
668610106510106790Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
161717212417192019202222234Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
121310131161210991311129Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
33433433333338Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
4133322213327Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212124222421192021212121256Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
102354689249870Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
311111111213Serine or threonine nucleophile; N-terminal nucleophile
9101010161613141191512145Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8712012480126119979897871141331,282Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
66727866632766Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33334322333335Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22222322332227Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
22531334434539Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
151014810911101191210129
1113
112
121222122116