Peptidases • White rot/brown rot example 2017
Annotations/GenomesAurde3_1Calco1Glotr1_1Phchr2TotalAnnotation Description
Merops
6223423153541,633
61273662186Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
12126Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
2022201678Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
916319Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
731213Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
4311119Water nucleophile; water bound by Gln and Glu; all endopeptidases
433515Families of peptidase inhibitors not assigned to clans
11
11
1113
322411
623314Families of metallopeptidases not assigned to clans
37915970Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1113Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
999936Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3423161588Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1910111050Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
546621Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
314Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2922222295Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
736622Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
213Serine or threonine nucleophile; N-terminal nucleophile
5312111288Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
195128112127562Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
18154340Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
353213Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
543416Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
11114
68211414117
11
11
93315